Der1-Like Domain Family, Member 3 (DERL3) Peptide
DERL3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN975732
Aperçu rapide pour Der1-Like Domain Family, Member 3 (DERL3) Peptide (ABIN975732)
Antigène
Derlin-3 (DERL3)
(Der1-Like Domain Family, Member 3 (DERL3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DERL3 antibody (Catalog #: ARP44443_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))
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Sujet
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DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL3 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM].
Alias Symbols: C22orf14, IZP6, MGC71803, LLN2, derlin-3
Protein Interaction Partner: MFI2,SERPINA1,AMFR
Protein Size: 235 -
Poids moléculaire
- 27 kDa
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ID gène
- 91319
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NCBI Accession
- NM_001002862, NP_001002862
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UniProt
- Q96Q80
Antigène
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